Exploring the enantiomeric 13C position-specific isotope fractionation: challenges and anisotropic NMR-based analytical strategy

Enantiomeric separation and compound specific stable isotope analysis

11 A fast and simple method for authenticating raspberry flavors from food products was developed. The two enantiomers 12 of the compound (E)-α-ionone from raspberry flavor were separated on a chiral gas chromatographic column. Based on 13 the ratio of these two enantiomers the naturalness of a raspberry flavor can be evaluated due to the fact that a natural 14 flavor will consist almost exclus...

Isotope Effects, Isotope Separation and Isotope Fractionation

SYNTHESIS OF SOME SUBSTITUTED NAPHTHALENES VIA BENZYNE AND THEIR 13C-NMR AND 'H-NMR STUDIES

Aprotic diazotization of anthranilic acid with isoamylnitrite or amylnitrite gave benzenediazonium-2- carboxylate. Subsequent thermal decomposition of this diazonium salt (in situ) in 1,2-dichloroethane as a solvent at 85OC and in the presence of 2,5-diethyl-3,4-diphenylcyclopentadienonaes a trapping agent gave 1,4-diethyl-2, 3-diphenylnaphthalene in high yield, after loss of carbon monoxid...

Position-Specific Isotope Analysis by Isotopic NMR Spectrometry: New Insights on Environmental Pollution Studies

The common practice of measuring the change in isotope ratio for the whole molecule using isotope ratio measurement by mass spectrometry leads to the loss of significant information of potential interest, since it is the position-specific fractionation which most closely reflects the effect of physicochemical processes. We have shown for MTBE, a common ground water contaminant, that isotopic qu...

High-precision position-specific isotope analysis.

Intramolecular carbon isotope distributions reflect details of the origin of organic compounds and may record the status of complex systems, such as environmental or physiological states. A strategy is reported here for high-precision determination of 13C/12C ratios at specific positions in organic compounds separated from complex mixtures. Free radical fragmentation of methyl palmitate, a test...